如何制备反式-2-癸烯酸? ¹

反式-2-癸烯酸是一种有机中间体，可以通过不同的方法合成。以下是几种报道的制备方法：

报道一

将丙二酸、辛醛和蒸馏的吡咯烷在碱的存在下加热反应，得到反式-2-癸烯酸。

报道二

将丙二酸、辛醛和催化剂哌啶混合后加热回流，然后用乙醚萃取产物，经过纯化得到反式-2-癸烯酸。

报道三

将二溴乙酸、辛醛和SmI₂在THF溶液中反应，然后用HCl水溶液淬灭反应，通过萃取和纯化得到反式-2-癸烯酸。

参考文献

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