各位大神，请问谁知道文章中所描述的基因表达的标准化是如何计算的？为什么标准化后的值在0-15之间？感谢。
The recurrence score on a scale from 0 to 100 is derived from the referencenormalized expression measurements in four steps.
First, expression for each gene is normalized relative to the expression of the five reference genes (ACTB[the gene encoding b -actin], GAPDH, GUS, RPLP , and TFRC). Reference-normalized expression measurements range from 0 to 15, with a 1-unit increase reflecting approximately a doubling of RNA.
