base，富马酸加入乙腈中，加热，溶解，降温析晶，不同的投料比例都试过，出来的都是1：1的，溶剂也试过...
随便找了个WO专利,看看有没有参考价值
To a solution of 9- amino] phenoxy phosphinyl] methoxy] propyl] adenine (100 gms, 0.209 mol) in acetonitrile (1890 gms), fumaric acid (22 gms, 0.188 mol) was added and heated to reflux to dissolve the solids. The reaction mass was filtered in hot condition, cooled to 5°C and maintained for 16 hours. The product was isolated by filtration, rinsed with acetonitrile (707 gms), and dried under reduced pressure to get 92 gms of product as a white crystalline powder.
